This study investigated the potential benefit of urban vegetation in reducing heat-related hospital admission rates in Western Sydney. An urban climate model was used to predict the average summer daily mean (ASDM) temperature using ten different urban vegetation schemes ranging from relatively low vegetation through to leafy urban suburbs, to full revegetation schemes represented by grassland and forest. Correlations were established for two age groups 0-64 and 65 years plus between mean daily air temperature and hospital admission rates for dehydration (DEHY) and heat exposure (HEAT) based on historical hospital admission data from 1991 to 2009 in Western Sydney. It was found that the daily DEHY and HEAT admission rates for the 65 years plus group were well correlated with mean daily air temperature. The correlations were then applied to the weather data generated based on the ASDM temperature using the urban climate model for each of the ten vegetation schemes, in order to investigate the potential benefit of vegetation in reducing heat-related hospital admission rates. The results show that hospital admission rates are expected to reduce with increased urban vegetation for the 65 years plus group. When compared to the existing urban vegetation scheme, a leafy urban suburb was estimated to reduce the projected daily hospital admission rates for DEHY and HEAT by 15% and 30%, respectively. The results highlight the importance of promoting urban vegetation as a strategy for adapting our urban environments to the potential health consequences of extreme heat.